(I suppose a short form of the "side effects" question is "what's the splash damage like?" - given that essentially this would be in the interest of cutting out the splash damage that said assholes have on the people around them, and across the whole world in some cases, every single day... whether causing road accidents, withholding lifesaving care over bureaucratic quibbles, threatening wars, blowing up marketplaces... whatever...

If the answer is that they can't be removed without causing even worse domino effects, then the gut reaction would be to twist the dial round to 0.1% and hit it immediately with little more thought (to get rid of the very worst ~7 million, who hopefully the great majority of us can at least agree need de-clawing one way or another, and whose removal might not trigger too much knock-on drama; in a country like the UK that would be a not inconsiderable 65,000 or so, if the average is evenly spread, but if the density was fairly homogenous it would seem like a very weird statistical blip more than anything else... well, other than that it might be over-represented in prisoners, politicians, flash ceos, heartless bean counters and shady small time businessmen... The undertakers would have a very busy fortnight afterwards, but things would soon return to normal, after a round of minor internal investigations in a few places...

Maybe even just 0.01% if it can go that low. That'd still leave a lot of fairly high level dickheads around, but the really really bad ones would have been filtered, and it's possible very few people would be really too sad to see them go.)